Welcome to the Knight Alzheimer's Disease Research Center ADRC, HASD and ACS combined databases. This site is managed by the Data Management Biostatistics Core at Washington University School of Medicine in St. Louis. The goal of this site is to provide updated summaries from the ADRC, HASD and ACS cohorts by single or multiple modalities.

• Demographics tabs display the following information from the baseline cohort:

    Age
    Education
    Gender
    Race
    MMSE
    APOE4


• Single Modality tab displays the following information based on the number of participants by frequency:

    Clinical/Cognitive Assessments
    CSF LP
    MRI
    Amyloid PET
    TAU PET


• Double Modality tab compares the following by time interval (all participants have clinical assessments):

    CSF LP and MRI
    CSF LP and Amyloid PET
    CSF LP and TAU PET
    MRI and Amyloid PET
    MRI and TAU PET
    Amyloid PET and TAU PET


• Triple Modality tab compares the following by time interval (all participants have clinical assessments):

    CSF LP and MRI and Amyloid PET
    MRI and Amyloid PET and TAU PET
    Amyloid PET and TAU PET and CSF
    TAU PET and CSF and MRI


To request access to databases for your project, please follow the instructions found here: https://knightadrc.wustl.edu/Research/ResourceRequest.htm

To view related publications from the Data Management Biostatistics Core, please click here: https://pubmed.ncbi.nlm.nih.gov/collections/59779884/?sort=pubdate

Total of ADRC,HASD and ACS Combined

Baseline Demographics for ADRC,HASD and ACS clinical cohort

Active Demographics for ADRC,HASD and ACS clinical cohort
('Active' refers to participants who have had a clinical assessment in the past 18 months and who are expected to return for follow-up)

ACS Only(new)

Baseline Demographics for ACS clinical cohort

Active Demographics for ACS clinical cohort
('Active' refers to participants who have had a clinical assessment in the past 18 months and who are expected to return for follow-up)

Single Modality

Number of participants by frequency of clinical/cognitive assessments

Number of participants by frequency of CSF assessments

Number of participants by frequency of MRI assessments

Number of participants by frequency of Amyloid PET assessments

Number of participants by frequency of TAU PET assessments

Double Modality
(all participants have clinical assessments)

CSF + MRI

CSF + Amyloid PET

CSF + TAU PET

MRI + Amyloid PET

MRI + TAU PET

Amyloid PET + TAU PET

Triple Modality
(all participants have clinical assessments)

CSF + MRI + Amyloid PET

MRI + Amyloid PET + TAU PET

Amyloid PET + TAU PET + CSF

TAU PET + CSF + MRI

For additional assistance please contact us.

Data Management and Biostatistics Core
Division of Biostatistics - Dr. Chengjie Xiong's Lab
Washington University School of Medicine in St. Louis
660 S. Euclid Ave
St. Louis MO 63110

Emily Gremminger, Project Manager
egremminger@wustl.edu